Post

Bugworks Research Develops Antibiotic to Combat MDR Infections

Bugworks Research Develops Antibiotic to Combat MDR Infections

Headquartered in Saratoga, CA with subsidiaries in Bangalore, and Australia, Bugworks Research announced that the first human dose was administered in a phase 1 clinical trial. This trial to evaluate BWC0977, a next generation broad-spectrum, novel bacterial topoisomerase inhibitor (NBTI), was supported by Boston University’s CARB-X  — Combating Antibiotic-Resistant Bacteria Biopharmaceutical Accelerator — a global nonprofit entity.

BWC0977 is a highly potent, intravenous broad-spectrum antibiotic with the potential for oral administration for the treatment of serious multi drug resistant (MDR) gram-negative infections such as acinetobacter baumannii, and drug resistant gram-positive infections such as methicillin resistant staphylococci (MRSA) to mention a few. It can address many serious hospital and community infections and combat a broad spectrum of pathogens that are biothreats. It has the potential of becoming a breakthrough antibiotic, not seen since the 1960s reports Pharmabiz.

Lab; research
Bugworks has raised $34 million in venture capital.
The phase 1 clinical trial, is being conducted in Australia after a positive pre-IND meeting with the FDA and with approval from HREC in Australia.
“Bugworks represents one of four CARB-X programs conducting first-in-human trials this year,” said Dr. Erin Duffy, chief of R&D, CARB-X. “We are proud to have accelerated this program from a lead optimization campaign through to this study to demonstrate safety and drug levels in healthy humans. C0977 has the potential to cover a broad range of priority pathogens in the syndromes of high unmet need.”
Share

About Amritt

Who We Are

Small or big, your business will love our financial help and business consultations! We are happy when our clients are too… Actually, this is quite simple to achieve – because each time we help them in sorting out different accounting intricacies or save the day before filing the taxes, they are happy indeed! And so are we.   

We have over Twenty years of experience helping our clients succeed in India

Generic selectors
Exact matches only
Search in title
Search in content
Post Type Selectors
Blog
Page
Dictionary
Comparisons
Capabilities
India Business Guide
Services
Private
Speaking
Insights
White Papers
News
Newsletters
Clients
Case Studies
Companies In India
Webinars
Presentations
Industries