The structure of a chemical compound has a strong relationship to the function and impacts of that compound on its environment. This is called the Structure-Activity Relationship(SAR), and scientists often use this data to predict the impacts of a potential new chemical compound. Scientists can use SAR Analysis tools to detect specific functional groups and their impacts, which can be modified to make changes to the function of the compound.
Oftentimes, lead optimization looks to alter many factors at once, which can overwhelm the capabilities of an individual medicinal chemist. SAR Analysis can greatly speed up the drug discovery process by predicting the behavior of different compounds, without needing to create each one. By systematically exploring and understanding how modifications in the molecular structure impact the biological response, scientists can design and tailor molecules with enhanced bioactivity and reduced side effects. Forward-thinking Western companies can turn to low-cost countries, such as India, to stretch their investment dollars and shorten development time, while still maintaining a high level of quality. Due to India’s long chemical history and skilled Indian technicians, technologically savvy Indian chemists can do a great job scaling up SAR analysis abroad for a much lower dollar amount.
SAR Analysis and models cannot be operated without knowledgeable chemists to properly interpret them. India is consistently graduating large numbers of PhDs who are experienced in these studies. Indian companies have a high capacity to conduct this type of work. If you are looking to save money and time by sending some of your tasks abroad, Amritt can help you choose the proper CDMO to fit the scale and needs of your individual organization.