Development and Reproductive Toxicology (DART) Studies are long-term studies that are used to detect any adverse impact of a potential drug candidate. DART studies examine a population throughout the entire reproductive process. They study fertility, embryotoxicity, and post-natal toxicity in organisms such as rats, mice and rabbits.
DART studies frequently require many groups of mature adults and juveniles in order to view impacts on the different stages of life. Because of this, DART studies can take long periods of time, be complex and expensive to operate, and be unpredictable due to uncontrollable variations in the mating processes. Enterprising Western companies can take advantage of resources abroad to minimize costs of this important step in the drug discovery process. Indian companies have state-of-the-art equipment, allowing for the same quality of work to be done at a much lower cost, as professional labor and technicians are cheaper in India. The monetary cost is just one of many benefits of working with Indian CDMOs. With larger facilities and vivariums, Indian organizations often can have higher capacities for holding organisms, which allows for a more efficient scale-up of these important toxicology studies.
There are many different CDMOs to choose from if you are looking to take your business to India, and with Amritt’s experience in choosing and managing partners across India, we can help you select the one that is perfectly suited to meet your company’s needs.