Absorption, Distribution, Metabolism, and Excretion(ADME) Assays play a vital role in bio-pharmaceutical research and drug development. For early stage companies funded by grants, angels, and venture investors, these assays are important to evaluate the pharmacokinetic profile of potential drug candidates. ADME can be a significant component of the cost of development, as well as the calendar time taken to identify viable drug candidates.
Innovative Western businesses can stretch their investment dollars and shorten development time by leveraging global resources from low-cost countries. In particular, India offers a large talent pool of qualified researchers at world-class quality.
Assessing ADME properties is essential to ensure that a drug candidate can reach its target site in sufficient concentrations to exert the desired effects, while also minimizing potential toxicity. ADME Assays are both done in-vitro and in-vivo. ADME assays are also required by the US Food and Drug Administration (FDA) and other regulators, such as the European Medicines Agency (EMA), so conducting these assays are vital to passing any Investigational New Drug through the drug discovery process.
Indian companies have large vivariums and state-of-the-art lab facilities, spanning millions of square feet. Western companies can build or buy their own facilities, or they can work with outsource partners vetted and managed by Amritt, without the need to travel across 9-12 time zones.
Companies in multiple locations in India are knowledgeable and experienced in ADME Assays. Amritt works closely with many of these companies and can help you decide who you can trust to conduct this important research on the ground.